The Azzurri will face England in the final at Wembley on Sunday, bidding to win their second European Championship title and first since Zoff helped the team to victory in 1968.
Spinazzola, 28, was stretchered off after 79 minutes and is expected to be sidelined for several months.
Insigne credited coach Roberto Mancini for building a "fun" atmosphere around the national team squad that has allowed him to put in his best performances.
Juventus held on to win 2-1 at Napoli in a stormy top-of-the-table clash on Sunday which saw both teams have a player sent off.
Napoli places third in their Champions League group with six points, three points behind Shakhtar Donetsk.
Napoli’s winger Lorenzo Insigne spoke on August 23 about his recent transfer news linking him to a move to FC Barcelona.