Koeman and his players are expecting a tough night in Bilbao when they face the city’s giants, Athletic Bilbao.
Messi returned to Barcelona’s squad for the match against Huesca after missing the team’s draw with Eibar last week.
Koeman said his side would find it difficult to win the La Liga title after they ended a traumatic 2020 with a 1-1 draw at home to minnows Eibar on Tuesday.
Coutinho is set to undergo knee surgery after sustaining an injury during Tuesday’s 1-1 draw with Eibar, the Spanish club said on Wednesday.
Koeman has called Valencia a difficult club to manage as he prepares to face his former team for the first time.
Lionel Messi scored his team’s winning goal over Levante after 75 minutes to save Barcelona from another negative result.
Barcelona out-classed Ferencvaros and eased their way to a 3-0 away win on Wednesday for a fifth consecutive Champions League victory.
Font believes luring former midfield great Xavi Hernandez back to the club would spark another golden age for the Catalans.
Messi came off the bench to score twice and lead Barcelona to a 5-2 home victory over Real Betis on Saturday.
Koeman cursed his side’s profligacy after they drew 1-1 at Alaves on Saturday, dropping points for the fourth game in a row in La Liga.
Neto made an embarrassing gaffe as his side were held to a 1-1 draw away to Alaves on Saturday, despite playing the final half an hour with an extra man.
Koeman was fiercely critical of the referee and video assistant after his side were beaten 3-1 at home to Real Madrid in Saturday’s ‘Clasico’ in La Liga.
Koeman insisted the club does not have a problem with Antoine Griezmann ahead of Saturday’s Clasico showdown with Real Madrid.
Lionel Messi became the first player to score in 16 consecutive Champions League seasons as he guided 10-man Barcelona to a 5-1 victory over Hungarian side Ferencvaros.
Koeman believes that the player is happy, focused and determined to do his best for the club.
Fati scored three out of Barcelona’s eight goals this season in the league and he booked a place in Koeman’s starting eleven.
Koeman says Messi has been the ideal captain and an example to the rest of the team for the way he has applied himself since deciding to stay at the club.
Impressive performances from Lionel Messi and Ansu Fati helped Barcelona overcome an early red card to defender Clement Lenglet and win 3-0 at Celta Vigo
Barcelona have completed the signing of United States full back Sergino Dest from Ajax Amsterdam for 21 million euros (19 million pounds).
Barcelona witnessed a great conflict this summer between Messi and the club president Josep Maria Bartomeu.