The Uruguayan striker returns to Barcelona cathedral, Camp Nou, as Barcelona host Atletico Madrid in La Liga title showdown.
Busquets has been ruled out of Saturday’s La Liga clash away to Atletico Madrid due to a knee injury sustained on international duty with Spain.
Cavani scored early and fellow striker Luis Suarez converted a second-half penalty, his fourth in three games for his country, as they beat Colombia 3-0.
Atletico Madrid’s Diego Costa is being treated for a thigh injury sustained against Centa Vigo at the weekend, the club confirmed on Monday.
Suarez has said he was reduced to tears by Barcelona’s treatment of him in his final weeks at the club.
The German giants are the favourites to advance to the semi-finals after clinching the domestic double.
Barcelona insist they have as much chance as Bayern Munich of winning their Champions League quarter-final despite a far from convincing 3-1 win over Napoli on Saturday.
Barcelona's victory sent bottom-of-the-table Espanyol to the second division for the first time in 27 years.
When La Liga stopped they were not expected to play any part in the rest of the title race but when the season resumes on Thursday, Eden Hazard and Luis Suarez could be set to decide it.
Rakitic arrived to the Catalans in 2014 summer from Sevilla and he was accompanied by many newcomers including, Luis Suarez and Marc Andre ter Stegen.
The Argentinian star has sustained an adductor injury and he is expected to miss the club's first game after LaLiga return against Real Mallorca.
The football suspension due to coronavirus pandemic was a great chance for the Uruguayan to have time to recover and be ready to help the team.
The Danish striker is expected to take part in the biggest game of the season, El Clasico, scheduled on Sunday night in Madrid.
Liverpool defeated Watford 2-0 to keep their winning streak a live and gain another three points in their run to win the long-awaited Premier League title.
The three players known as MSG scored for the first time in a single game and their partnership started to click.
Barcelona players aim to bounce back after suffering a 1-0 loss against Athletic Bilbao at the opening game of the league
The draw saw Barca's advantage over nearest challengers Atletico Madrid reduced to eight points ahead of Saturday's showdown at home to Diego Simeone's side.
Suarez will be out action for two weeks after he picked an injury during the last minutes of Barcelona game against Real Betis on Sunday night at the League.
Luis Suarez said Barcelona had honoured the club's reputation as insatiable trophy collectors after scoring twice in a 3-0 win at rivals Real Madrid on Wednesday to reach the Copa del Rey final for an astonishing sixth straight season.
The Uruguayan scored 15 Liga goals but has not found the net in a Champions League away game since a 1-1 draw at AS Roma in September 2015