Federer will face a "reality check" when he returns to the Tour after a lengthy injury break, seven-time major champion Mats Wilander said.
Djokovic has signed up for both singles and doubles duty at next week's Paris Masters.
His withdrawal from the mixed doubles means Ash Barty and John Peers bag a bronze medal for Australia.
Djokovic has now won 18 consecutive matches this season in a period that has seen him lift the ATP Cup trophy for Serbia and his eighth Australian Open crown as well as Dubai, and he now holds 79 career titles.
The 21-year-old German, ranked fourth in the world, is part of the highly-touted "NextGen" crop of 20-somethings who are making an impact on the ATP Tour.
Novak Djokovic is the overwhelming favourite to secure a fourth Wimbledon title on Sunday but he admits he feared his best days were behind him when his career nose-dived over the last year.
"I think the biggest challenge will always be mental," Djokovic told British media.
After being treated for neck pain during that match, the 12-times Grand Slam winner cast doubts on his Wimbledon participation following his Roland Garros exit.
The downpours also prevented two-time champion Maria Sharapova from starting her opener against Richel Hogenkamp of the Netherlands.
Novak Djokovic has parted company with coach Radek Stepanek days after the departure of head coach Andre Agassi from his team.
Roger Federer suffered a shock 3-6 6-3 7-6(4) defeat to Australian wildcard Thanasi Kokkinakis on Saturday
Former world number one Novak Djokovic withdrew from next week's Qatar Open on Saturday
Former world number ones Andy Murray and Novak Djokovic are relishing their return to competition.
Novak Djokovic, Serbian tennis player, announced on Wednesday that he will not compete in the remaining competitions in the season due to injury.
Second seed Djokovic's fourth-round match against France's Adrian Mannarino was pushed back from Monday due to the epic five.
Centre Court fans at Wimbledon will be hoping to see a bit more of Novak Djokovic and Roger Federer on Saturday when they play back-to-back third round matches.
Novak Djokovic effectively waved the white flag, bowing out of the French Open with a whimper on Wednesday.
The Roland Garros (French Open), one of four grand slam tournaments in tennis, officially kicked off in Paris Sunday.
Results from the French Open Men's Singles Round 1 matches on Monday.