The Uruguayan striker returns to Barcelona cathedral, Camp Nou, as Barcelona host Atletico Madrid in La Liga title showdown.
The three clubs still involved in the proposed European Super League, denounced on Saturday the "intolerable" pressure put on them by UEFA to drop the project.
United fans last week breached security at the club's training ground as they protested against the Glazer family for their role in the Super League plot
Messi's brace took him to the 25-goal mark, which he hit for the 12th season in a row.
Los Blancos came out victorious in both matches and they are now preparing for the second leg of the Champions League quarter-finals, scheduled on Wednesday.
Messi is not expected to consider offers to renew his contract until the end of the season but Laporta has been pulling hard on the heart-strings.
ElClásico is one of the longest-running and heated rivalries in world football and LaLiga's activations highlight the passion and intensity of the game.
Barcelona aim to get the three points and keep chasing the leaders, Atletico Madrid, who are topping the table with 4 clear points.
Both teams will face off for the first time since the 2018 UEFA Champions League final in Kiev, which ended with a 3-1 win for the Spanish giants.
Lionel Messi and co will be out of the competition's quarter-finals for the first time since 2006-2007 season.
Real are already without Dani Carvajal, Eden Hazard and captain Sergio Ramos for the trip across the Spanish capital.
Koeman praised his side for their never-say-die attitude after they reached the Copa del Rey final with a 3-0 win after extra-time over Sevilla.
Paris St Germain forward Neymar's return from injury is on schedule after he was ruled out for four weeks earlier this month with an adductor muscle injury.
Mascherano shared the dressing room with Messi in Barcelona between 2010 and 2018.
Yaya Toure has been named assistant manager of Olimpik Donetsk, the Ukrainian Premier League club said on Wednesday.
Athletic Club face Barcelona on Sunday night in the competition’s final at La Cartuja stadium in Seville.
FC Barcelona will hold talks with the regional Catalan government on Friday over whether or not to hold its upcoming election as planned.
Koeman and his players are expecting a tough night in Bilbao when they face the city’s giants, Athletic Bilbao.
Messi returned to Barcelona’s squad for the match against Huesca after missing the team’s draw with Eibar last week.
Koeman said his side would find it difficult to win the La Liga title after they ended a traumatic 2020 with a 1-1 draw at home to minnows Eibar on Tuesday.