Dortmund, who travel to Chelsea on Tuesday for their Champions League Round of 16 second leg leading 1-0, have improved their club record with their best start of the year, even better than in their 2011/12 title-winning season.
Adeyemi broke from inside his own half and sprinted more than 60 metres before slotting home to give Dortmund a win in the first leg of their last 16 tie.
Dortmund start the weekend second in the table and nine points behind runaway Bundesliga leaders Bayern Munich, but with a game in hand.
Borussia Dortmund coach Marco Rose said Saturday that injured star striker Erling Haaland will remain sidelined for Sunday's game against Borussia Moenchengladbach.
On Monday, the exact nature of the injury and the length of his absence were still unknown.
Etienne Amenyido gave St Pauli a fourth-minute lead from close range and Axel Witsel's own goal in the 40th minute doubled the hosts' advantage.
Haaland is set to make a surprise return for Borussia Dortmund this weekend after a five-week absence with a leg injury.
Haaland has ruled himself out of Borussia Dortmund's Bundesliga match against Augsburg on Saturday and is set to miss Norway's upcoming World Cup qualifiers.
Marco Rose says he will do everything to keep Bellingham and Haaland at the Bundesliga club as the young stars attract the attention of Europe's top clubs.
On April 19, many important events that changed the world map took place.
Sancho, a product of City's academy, rejected a new contract at the Premier League club when he was 17 to join Dortmund in 2017.
Despite missing a month with injury, Haaland, 20, has managed 17 league goals this season, but admits there is "a lot" he can learn from Lewandowski
Southgate said he could hand Borussia Dortmund teenager Jude Bellingham his first cap when they host Ireland on Thursday.
POOL/AFP / Lars Baron
Joshua Kimmich described his winning goal as "brutally important" after Bayern Munich took a huge step towards an eighth straight Bundesliga title on Tuesday with a 1-0 win at Borussia Dortmund to leave them seven points clear at the top with just six gam
Real Madrid showed interest in signing the player, who took the Bundesliga by storm since he signed for Dortmund last winter.
Bundesliga leaders Borussia Dortmund are hoping captain Marco Reus will be fit for Sunday's match against in-form Bayer Leverkusen as they look to reignite their stalled title run.
Defender Jan Vertonghen scored once and set up another goal for Son Heung-min as Tottenham Hotspur thumped Borussia Dortmund 3-0 at Wembley Stadium on Wednesday to give them the clear edge following the first leg of their last 16 Champions League tie.
Ribery issued a public apology to French television pundit Patrick Guillou, who he reportedly insulted and assaulted following Bayern Munich's away defeat to Borussia Dortmund
Borussia Dortmund have agreed to sign Belgium international Axel Witsel from Chinese side Tianjin Quanjian, the German club said on Monday.